Description
Dapoxetine is a short-acting antidepressant (SSRI) that is used specifically to treat premature ejaculation (PE) in men.
What it is
- Drug class: Selective Serotonin Reuptake Inhibitor (SSRI)
- Unlike regular SSRIs, dapoxetine is taken only when needed, not daily.
- It was developed only for sexual dysfunction, not for depression.
What it’s used for
- Premature ejaculation (lifelong or acquired)
- Helps delay ejaculation and improve control
- Often improves sexual satisfaction for both partners
How it works
- Increases serotonin activity in the nervous system
- Serotonin slows the ejaculatory reflex
- Acts quickly and leaves the body fast (short half-life)
How it’s taken
- Usually 30 mg or 60 mg
- Taken 1–3 hours before sexual activity
- Not more than once per day
Common side effects
- Nausea
- Dizziness
- Headache
- Diarrhea
- Insomnia
- Fatigue
Less common but important:
- Drop in blood pressure
- Fainting (especially when combined with alcohol)
Important warnings
- Do NOT combine with alcohol
- Caution if you have:
- Heart problems
- Low blood pressure
- Liver disease
- Should not be mixed with:
- Other SSRIs / antidepressants
- MAO inhibitors
- Certain painkillers or recreational drugs
Legal / availability note
- Approved in many countries
- Not FDA-approved in the USA, but still commonly used elsewhere
- Often sold under brand names like Priligy
In short
Dapoxetine is an on-demand medication for premature ejaculation, designed to work fast and clear quickly, unlike standard antidepressants.







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