Dapoxetin

Description

Dapoxetine is a short-acting antidepressant (SSRI) that is used specifically to treat premature ejaculation (PE) in men.

What it is

• Drug class: Selective Serotonin Reuptake Inhibitor (SSRI)
• Unlike regular SSRIs, dapoxetine is taken only when needed, not daily.
• It was developed only for sexual dysfunction, not for depression.

What it’s used for

• Premature ejaculation (lifelong or acquired)
• Helps delay ejaculation and improve control
• Often improves sexual satisfaction for both partners

How it works

• Increases serotonin activity in the nervous system
• Serotonin slows the ejaculatory reflex
• Acts quickly and leaves the body fast (short half-life)

How it’s taken

• Usually 30 mg or 60 mg
• Taken 1–3 hours before sexual activity
• Not more than once per day

Common side effects

• Nausea
• Dizziness
• Headache
• Diarrhea
• Insomnia
• Fatigue

Less common but important:

• Drop in blood pressure
• Fainting (especially when combined with alcohol)

Important warnings

• Do NOT combine with alcohol
• Caution if you have:
  • Heart problems
  • Low blood pressure
  • Liver disease
• Should not be mixed with:
  • Other SSRIs / antidepressants
  • MAO inhibitors
  • Certain painkillers or recreational drugs

Legal / availability note

• Approved in many countries
• Not FDA-approved in the USA, but still commonly used elsewhere
• Often sold under brand names like Priligy

In short

Dapoxetine is an on-demand medication for premature ejaculation, designed to work fast and clear quickly, unlike standard antidepressants.